CRANAD 2

Code: SML0842-25MG D2-231

Biochem/physiol Actions

CRANAD 2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for A...


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€501.10 25MG
€616.35 inc. VAT
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Biochem/physiol Actions

CRANAD 2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM. Upon interacting with Aβ aggregates, CRANAD 2 exhibits a 70-fold increase in fluorescence intensity accompanied by a 90 nm blue shift from 805 to 715 nm and a large increase in quantum yield. CRANAD 2 has been used to detect Aβ deposits noninvasively in vivo in transgenic Tg2576 mice.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
color, dark blue to black
formpowder
Quality Level100
solubilityDMSO: 0.2 mg/mL, clear (warmed)
storage conditiondesiccated
storage temp.2-8°C
Cas Number1193447-34-5
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